Certified Gastroenterology Registered Nurse Practice Exam 2025 – Comprehensive All-in-One Guide for Exam Success

The statement regarding H2 blockers reducing stomach acid production accurately captures the primary mechanism of action of these medications in the treatment of gastroesophageal reflux disease (GERD), particularly in children. H2 blockers, such as ranitidine and famotidine, work by inhibiting the histamine H2 receptors on the parietal cells of the stomach's lining. This inhibition leads to a decrease in the secretion of gastric acid.

In cases of GERD, excessive stomach acid can contribute to the symptoms of reflux and esophagitis. By reducing the overall acidity in the stomach, H2 blockers help to alleviate the painful symptoms associated with GERD, such as heartburn and regurgitation. This acid-reducing effect makes it easier for the esophagus to heal and improves comfort for the child.

While other treatments may aim to enhance gastric motility or lubricate the esophagus, the specific function of H2 blockers is centered around controlling acid production, making option B the most accurate representation of their role in managing GERD in pediatric patients.

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